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Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry

HIV-1 enters target cells by virtue of envelope glycoprotein trimers that are incorporated at low density in the viral membrane. How many trimers are required to interact with target cell receptors to mediate virus entry, the HIV entry stoichiometry, still awaits clarification. Here, we provide esti...

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Publicado en:PLoS Pathog
Main Authors: Brandenberg, Oliver F., Magnus, Carsten, Rusert, Peter, Regoes, Roland R., Trkola, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287578/
https://ncbi.nlm.nih.gov/pubmed/25569556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004595
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