Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction

BACKGROUND: Natural killer (NK) cells play a key role in non-specific immune response in different cancers, including pancreatic cancer. However the anti-tumor effect of NK cells decreases during pancreatic cancer progression. The regulatory pathways by which NK cells facilitate tumor immune escape...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Peng, Yun-Peng, Zhang, Jing-Jing, Liang, Wen-biao, Tu, Min, Lu, Zi-Peng, Wei, Ji-Shu, Jiang, Kui-Rong, Gao, Wen-Tao, Wu, Jun-Li, Xu, Ze-Kuan, Miao, Yi, Zhu, Yi
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287420/
https://ncbi.nlm.nih.gov/pubmed/25274283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-738
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