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Persistent Production of an Integrase-Deleted HIV-1 Variant with No Resistance Mutation and Wild-Type Proviral DNA in a Treated Patient

An HIV-infected patient presenting an unexpected viral escape under combined antiretroviral treatment is described. The virus isolated from plasma contained a large deletion in the HIV-1 integrase gene but no known resistance mutation. Nested polymerase chain reactions (PCRs) with patient virus inte...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Trabaud, Mary-Anne, Cotte, Laurent, Saison, Julien, Ramière, Christophe, Ronfort, Corinne, Venet, Fabienne, Tardy, Jean-Claude, Monneret, Guillaume, André, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287311/
https://ncbi.nlm.nih.gov/pubmed/25333615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2014.0129
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