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An Improved Catalyst Architecture for Rhodium (III) Catalyzed C–H Activation and its Application to Pyridone Synthesis

We have developed a method for preparing pyridones from the coupling reaction of acrylamides and alkynes with either stoichometric Cu(OAc)(2) or catalytic Cu(OAc)(2) and air as oxidants. In the course of these studies, it was found that a larger ligand, 1,3-di-tert-butylcyclopentadienyl (termed Cp(t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Hyster, Todd K., Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286810/
https://ncbi.nlm.nih.gov/pubmed/25580208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1SC00235J
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