Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.
The Hoxd-11 gene was disrupted by homologous recombination in embryonic stem cells. We found that Hoxd-11-/- mutant mice are viable and display homeotic transformations of their sacral vertebrae, while their forelimbs present abnormalities of some metacarpals and of the first row of carpal bones. Th...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7816839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.1.310 |
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