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The homeodomain of Eyeless regulates cell growth and antagonizes the paired domain-dependent retinal differentiation function

Pax6 and its Drosophila homolog Eyeless (Ey) play essential roles during eye development. Ey/Pax6 contains two distinct DNA binding domains, a Paired domain (PD) and a Homeodomain (HD). While Ey/Pax6 PD is required for the expression of key regulators of retinal development, relatively little is kno...

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Publié dans:Protein Cell
Auteurs principaux: Tanaka-Matakatsu, Miho, Miller, John, Du, Wei
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286722/
https://ncbi.nlm.nih.gov/pubmed/25234589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0101-9
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