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Positional Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical Framework

The concept of positional information is central to our understanding of how cells determine their location in a multicellular structure and thereby their developmental fates. Nevertheless, positional information has neither been defined mathematically nor quantified in a principled way. Here we pro...

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Vydáno v:Genetics
Hlavní autoři: Tkačik, Gašper, Dubuis, Julien O., Petkova, Mariela D., Gregor, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286692/
https://ncbi.nlm.nih.gov/pubmed/25361898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.171850
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