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Mechanism of the αβ Conformational Change in F(1)-ATPase after ATP Hydrolysis: Free-Energy Simulations

One of the motive forces for F(1)-ATPase rotation is the conformational change of the catalytically active β subunit due to closing and opening motions caused by ATP binding and hydrolysis, respectively. The closing motion is accomplished in two steps: the hydrogen-bond network around ATP changes an...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Ito, Yuko, Ikeguchi, Mitsunori
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286612/
https://ncbi.nlm.nih.gov/pubmed/25564855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.1853
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