Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

Exercise, obesity and type 2 diabetes are associated with elevated plasma concentrations of interleukin-6 (IL-6). Glucagon-like peptide-1 (GLP-1) is a hormone that induces insulin secretion. Here we show that administration of IL-6 or elevated IL-6 concentrations in response to exercise stimulate GL...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Med
Egile Nagusiak: Ellingsgaard, Helga, Hauselmann, Irina, Schuler, Beat, Habib, Abdella M, Baggio, Laurie L, Meier, Daniel T, Eppler, Elisabeth, Bouzakri, Karim, Wueest, Stephan, Muller, Yannick D, Hansen, Ann Maria Kruse, Reinecke, Manfred, Konrad, Daniel, Gassmann, Max, Reimann, Frank, Halban, Philippe A, Gromada, Jesper, Drucker, Daniel J, Gribble, Fiona M, Ehses, Jan A, Donath, Marc Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286294/
https://ncbi.nlm.nih.gov/pubmed/22037645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2513
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