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A sharp thermal transition of fast aromatic ring dynamics in ubiquitin

Aromatic amino acid side chains have a rich role within proteins and are often central to their structure and function. Suitable isotopic labelling strategies enable studies of sub-nanosecond aromatic ring dynamics using solution NMR relaxation methods. Surprisingly, we find that the three aromatic...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Kasinath, Vignesh, Fu, Yinan, Sharp, Kim A., Wand, A. Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286287/
https://ncbi.nlm.nih.gov/pubmed/25476230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408220
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