The effect of Helicobacter pylori CagA on the HER-2 copy number and expression in gastric cancer

We investigated whether Helicobacter pylori (H. pylori) CagA contributes to the DNA copy change and mRNA transcript expression of the HER-2 gene and, consequently, affects HER-2 protein expression to evaluate the significance of CagA and HER-2 amplification in gastric cancer. We used the AGS andMKN1...

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Bibliografske podrobnosti
izdano v:Gene
Main Authors: Shim, Jung Ho, Yoon, Jung Hwan, Choi, Sung Sook, Ashktorab, Hassan, Smoot, Duane T., Song, Kyo Young, Nam, Suk Woo, Lee, Jung Young, Park, Cho Hyun, Park, Won Sang
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286173/
https://ncbi.nlm.nih.gov/pubmed/24879917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.05.064
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