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Altered brain protein expression profiles are associated with molecular neurological dysfunction in the PKU mouse model

Phenylketonuria (PKU), if not detected and treated in newborns, causes severe neurological dysfunction and cognitive and behavioral deficiencies. Despite the biochemical characterization of PKU, the molecular mechanisms underlying PKU-associated brain dysfunction remain poorly understood. The aim of...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Imperlini, Esther, Orrù, Stefania, Corbo, Claudia, Daniele, Aurora, Salvatore, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286000/
https://ncbi.nlm.nih.gov/pubmed/24548049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12683
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