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Altering the Divalent Metal Ion Preference of RNase E

RNase E is a major intracellular endoribonuclease in many bacteria and participates in most aspects of RNA processing and degradation. RNase E requires a divalent metal ion for its activity. We show that only Mg(2+) and Mn(2+) will support significant rates of activity in vitro against natural RNAs,...

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Thompson, Katharine J., Zong, Jeff, Mackie, George A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285977/
https://ncbi.nlm.nih.gov/pubmed/25404697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02372-14
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