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A PRIM approach to predictive-signature development for patient stratification

Patients often respond differently to a treatment because of individual heterogeneity. Failures of clinical trials can be substantially reduced if, prior to an investigational treatment, patients are stratified into responders and nonresponders based on biological or demographic characteristics. The...

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Publicat a:Stat Med
Autors principals: Chen, Gong, Zhong, Hua, Belousov, Anton, Devanarayan, Viswanath
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285951/
https://ncbi.nlm.nih.gov/pubmed/25345685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6343
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