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Simultaneous decomposition of multiple hyperspectral data sets: signal recovery of unknown fluorophores in the retinal pigment epithelium

Upon excitation with different wavelengths of light, biological tissues emit distinct but related autofluorescence signals. We used non-negative matrix factorization (NMF) to simultaneously decompose co-registered hyperspectral emission data from human retinal pigment epithelium/Bruch’s membrane spe...

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Publicat a:Biomed Opt Express
Autors principals: Smith, R. Theodore, Post, Robert, Johri, Ansh, Lee, Michele D., Ablonczy, Zsolt, Curcio, Christine A., Ach, Thomas, Sajda, Paul
Format: Artigo
Idioma:Inglês
Publicat: Optical Society of America 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285597/
https://ncbi.nlm.nih.gov/pubmed/25574430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.5.004171
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