Pilot study of Biomarkers for predicting effectiveness of ramosetron in diarrhea-predominant irritable bowel syndrome: expression of S100A10 and polymorphisms of TPH1

BACKGROUND: Serotonin type 3 receptor (5-HT(3)R) antagonists are potentially useful therapeutic agents for diarrhea-predominant irritable bowel syndrome (IBS-D). AIM: To identify biomarkers predicting effectiveness of the 5-HT(3)R antagonist (ramosetron) in IBS-D. METHODS: IBS-D Japanese subjects re...

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Vydáno v:Neurogastroenterol Motil
Hlavní autoři: Shiotani, Akiko, Kusunoki, Hiroaki, Ishii, Mnabu, Imamura, Hiroshi, Manabe, Noriaki, Kamada, Tomoari, Hata, Jiro, Merchant, Juanita, Haruma, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285583/
https://ncbi.nlm.nih.gov/pubmed/25428414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12473
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