Loss of expression of the cancer stem cell marker aldehyde dehydrogenase1 correlates with advanced stage colorectal cancer

BACKGROUND: Colorectal cancer (CRC) progression is mediated by cancer stem cells (CSCs). We sought to determine if expression of the CSC marker aldehyde dehydrogenase 1 (ALDH1) in CRC tumors varies by AJCC stage or correlates to clinical outcomes. METHODS: Primary and metastatic CRC samples from 96...

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Veröffentlicht in:Am J Surg
Hauptverfasser: Hessman, Crystal J., Bubbers, Emily J., Billingsley, Kevin G., Herzig, Daniel O., Wong, Melissa H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285581/
https://ncbi.nlm.nih.gov/pubmed/22405917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2012.01.003
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