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Crucial Role of IL1beta and C3a in the In Vitro-Response of Multipotent Mesenchymal Stromal Cells to Inflammatory Mediators of Polytrauma

Multipotent mesenchymal stromal cells (MSC) exert immune-modulatory effects and support tissue regeneration in various local trauma models. In case of a polytrauma, high amounts of danger-associated molecular patterns are released, leading to a systemic increase of inflammatory mediators. The influe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hengartner, Nina-Emily, Fiedler, Jörg, Schrezenmeier, Hubert, Huber-Lang, Markus, Brenner, Rolf E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285554/
https://ncbi.nlm.nih.gov/pubmed/25562599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116772
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