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Nedd8 Regulates Inflammasome-Dependent Caspase-1 Activation
Caspase-1 is activated by the inflammasome complex to process cytokines like interleukin-1β (IL-1β). Pro-caspase-1 consists of three domains, CARD, p20, and p10. Association of pro-caspase-1 with the inflammasome results in initiation of its autocatalytic activity, culminating in self-cleavage that...
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| 出版年: | Mol Cell Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285429/ https://ncbi.nlm.nih.gov/pubmed/25452302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00775-14 |
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