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Inactivation of Tristetraprolin in Chronic Hypoxia Provokes the Expression of Cathepsin B

Macrophages play important roles in many diseases and are frequently found in hypoxic areas. A chronic hypoxic microenvironment alters global cellular protein expression, but molecular details remain poorly understood. Although hypoxia-inducible factor (HIF) is an established transcription factor al...

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Publicado en:Mol Cell Biol
Main Authors: Fuhrmann, Dominik C., Tausendschön, Michaela, Wittig, Ilka, Steger, Mirco, Ding, Martina G., Schmid, Tobias, Dehne, Nathalie, Brüne, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285428/
https://ncbi.nlm.nih.gov/pubmed/25452305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01034-14
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