INTERACTIONS BETWEEN EXTRACELLULAR SIGNAL-REGULATED KINASE 1/2 AND P38 MAP KINASE PATHWAYS IN THE CONTROL OF RUNX2 PHOSPHORYLATION AND TRANSCRIPTIONAL ACTIVITY

RUNX2, a key transcription factor for osteoblast differentiation, is regulated by ERK1/2 and p38 MAP kinase-mediated phosphorylation. However, the specific contribution of each kinase to RUNX2-dependent transcription is not known. Here we investigate ERK and p38 regulation of RUNX2 using a unique P-...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Ge, Chunxi, Yang, Qian, Zhao, Guisheng, Yu, Hong, Kirkwood, Keith L., Franceschi, Renny T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285380/
https://ncbi.nlm.nih.gov/pubmed/22072425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.561
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