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Specific analogues uncouple transport, signalling, oligo-ubiquitination and endocytosis in the yeast Gap1 amino acid transceptor

The Saccharomyces cerevisiae amino acid transceptor Gap1 functions as receptor for signalling to the PKA pathway and concomitantly undergoes substrate-induced oligo-ubiquitination and endocytosis. We have identified specific amino acids and analogues that uncouple to certain extent signalling, trans...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Van Zeebroeck, Griet, Rubio-Texeira, Marta, Schothorst, Joep, Thevelein, Johan M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285233/
https://ncbi.nlm.nih.gov/pubmed/24852066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12654
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