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Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients’ antibodies react with the N-terminal domain of the GluN1 (previously known as NR1) subunit of NMDAR causing in cultured neurons a se...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Planagumà, Jesús, Leypoldt, Frank, Mannara, Francesco, Gutiérrez-Cuesta, Javier, Martín-García, Elena, Aguilar, Esther, Titulaer, Maarten J., Petit-Pedrol, Mar, Jain, Ankit, Balice-Gordon, Rita, Lakadamyali, Melike, Graus, Francesc, Maldonado, Rafael, Dalmau, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285189/
https://ncbi.nlm.nih.gov/pubmed/25392198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu310
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