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Effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance

The heme-degrading enzyme heme oxygenase-1 (HO-1) has cytoprotective, antioxidant, and anti-inflammatory properties. Moreover, HO-1 is reportedly involved in suppressing destructive immune responses associated with inflammation, autoimmune diseases, and allograft rejection. During pregnancy, materna...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Schumacher, Anne, Zenclussen, Ana C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285018/
https://ncbi.nlm.nih.gov/pubmed/25610397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00288
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