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DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers
BACKGROUND: A shift between two dimer conformations has been proposed for the transcription factor STAT1 (signal transducer and activator of transcription 1) which links DNA binding of the parallel dimer to tyrosine dephosphorylation of the antiparallel dimer as two consecutive and important steps i...
में बचाया:
| में प्रकाशित: | BMC Biochem |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284922/ https://ncbi.nlm.nih.gov/pubmed/25526807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-014-0028-z |
| टैग : |
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