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Identification of the xenosensors regulating human 5-aminolevulinate synthase
Heme is an essential component of numerous hemoproteins with functions including oxygen transport, energy metabolism, and drug biotransformation. In nonerythropoietic cells, 5-aminolevulinate synthase (ALAS1) is the rate-limiting enzyme in heme biosynthesis. Upon exposure to drugs that induce cytoch...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC428484/ https://ncbi.nlm.nih.gov/pubmed/15178759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401845101 |
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