High-quality genome (re)assembly using chromosomal contact data

Closing gaps in draft genome assemblies can be costly and time-consuming, and published genomes are therefore often left ‘unfinished.’ Here we show that genome-wide chromosome conformation capture (3C) data can be used to overcome these limitations, and present a computational approach rooted in pol...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Marie-Nelly, Hervé, Marbouty, Martial, Cournac, Axel, Flot, Jean-François, Liti, Gianni, Parodi, Dante Poggi, Syan, Sylvie, Guillén, Nancy, Margeot, Antoine, Zimmer, Christophe, Koszul, Romain
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284522/
https://ncbi.nlm.nih.gov/pubmed/25517223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6695
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