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Thyrotropin and Obesity: Increased Adipose Triglyceride Content Through Glycerol-3-Phosphate Acyltransferase 3

Epidemiological evidence indicates that thyrotropin (TSH) is positively correlated with the severity of obesity. However, the mechanism remains unclear. Here, we show that TSH promoted triglyceride (TG) synthesis in differentiated adipocytes in a thyroid hormone-independent manner. Mice with subclin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Shizhan, Jing, Fei, Xu, Chao, Zhou, Lingyan, Song, Yongfeng, Yu, Chunxiao, Jiang, Dongqing, Gao, Ling, Li, Yujie, Guan, Qingbo, Zhao, Jiajun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284501/
https://ncbi.nlm.nih.gov/pubmed/25559747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07633
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