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Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability

Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid–specific transcription but has distinct roles in oocyte meiotic p...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Pattabiraman, Shrivatsav, Baumann, Claudia, Guisado, Daniela, Eppig, John J., Schimenti, John C., De La Fuente, Rabindranath
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284233/
https://ncbi.nlm.nih.gov/pubmed/25547156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404109
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