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Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability

Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid–specific transcription but has distinct roles in oocyte meiotic p...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Pattabiraman, Shrivatsav, Baumann, Claudia, Guisado, Daniela, Eppig, John J., Schimenti, John C., De La Fuente, Rabindranath
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284233/
https://ncbi.nlm.nih.gov/pubmed/25547156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404109
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