Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability

Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid–specific transcription but has distinct roles in oocyte meiotic p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Pattabiraman, Shrivatsav, Baumann, Claudia, Guisado, Daniela, Eppig, John J., Schimenti, John C., De La Fuente, Rabindranath
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284233/
https://ncbi.nlm.nih.gov/pubmed/25547156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404109
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