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Assessment of fully automated antibody homology modeling protocols in molecular operating environment

The success of antibody-based drugs has led to an increased demand for predictive computational tools to assist antibody engineering efforts surrounding the six hypervariable loop regions making up the antigen binding site. Accurate computational modeling of isolated protein loop regions can be quit...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Maier, Johannes K X, Labute, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284016/
https://ncbi.nlm.nih.gov/pubmed/24715627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24576
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