From beat rate variability in induced pluripotent stem cell-derived pacemaker cells to heart rate variability in human subjects

BACKGROUND: We previously reported that induced Pluripotent Stem Cell-derived cardiomyocytes (iPSC-CM) manifest beat rate variability (BRV) resembling heart rate variability (HRV) in human sinoatrial node (SAN). We now hypothesized the BRV-HRV continuum originates in pacemaker cells. OBJECTIVE: To i...

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Dettagli Bibliografici
Pubblicato in:Heart Rhythm
Autori principali: Ben-Ari, Meital, Schick, Revital, Barad, Lili, Novak, Atara, Ben-Ari, Erez, Lorber, Avraham, Itskovitz-Eldor, Joseph, Rosen, Michael R, Weissman, Amir, Binah, Ofer
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283811/
https://ncbi.nlm.nih.gov/pubmed/25052725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2014.05.037
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