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A Bayesian approach for unplanned sample sizes in phase II cancer clinical trials
BACKGROUND: Phase II cancer clinical trials commonly employ two-stage designs that incorporate a single interim analysis for lack of efficacy and are designed to achieve specified frequentist properties. The requirement to examine the outcome at a prespecified sample size (SS) can be problematic, be...
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| Publicat a: | Clin Trials |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283461/ https://ncbi.nlm.nih.gov/pubmed/22523304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774512443429 |
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