Prostaglandin D(2)-supplemented “functional eicosanoid testing and typing” assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease: an explorative diagnostic study

BACKGROUND: Systemic mast cell activation disease (MCAD) is characterized by an enhanced release of mast cell-derived mediators, including eicosanoids, which induce a broad spectrum of clinical symptoms. Accordingly, the diagnostic algorithm of MCAD presupposes the proof of increased mast cell media...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Schäfer, Dirk, Dreßen, Peter, Brettner, Stefan, Rath, Norbert-Folke, Molderings, Gerhard J, Jensen, Katrin, Ziemann, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283146/
https://ncbi.nlm.nih.gov/pubmed/25113638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0213-2
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