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Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children’s Oncology Group

PURPOSE: We explored the impact of obesity, body composition, and genetic polymorphisms on the pharmacokinetics (PK) of daunorubicin in children with cancer. PATIENTS AND METHODS: Patients ≤21 years receiving daunorubicin as an infusion of any duration <24 h for any type of cancer were eligible....

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Thompson, Patrick, Wheeler, Heather E., Delaney, Shannon M., Lorier, Rachel, Broeckel, Ulrich, Devidas, Meenakshi, Reaman, Gregory H., Scorsone, Kathleen, Sung, Lillian, Dolan, M. Eileen, Berg, Stacey L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282931/
https://ncbi.nlm.nih.gov/pubmed/25119182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2535-4
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