Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression

BACKGROUND: Immunogenetic evidence indicates that cytotoxic T lymphocytes (CTLs) specific for the weak CTL antigen HBZ limit HTLV-1 proviral load in vivo, whereas there is no clear relationship between the proviral load and the frequency of CTLs specific for the immunodominant antigen Tax. In vivo,...

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Vydáno v:Retrovirology
Hlavní autoři: Rowan, Aileen G, Suemori, Koichiro, Fujiwara, Hiroshi, Yasukawa, Masaki, Tanaka, Yuetsu, Taylor, Graham P, Bangham, Charles RM
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282740/
https://ncbi.nlm.nih.gov/pubmed/25499803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0116-6
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