Prostaglandin E(2)/Leukotriene B(4) balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection

BACKGROUND: Eicosanoids and sand fly saliva have a critical role in the Leishmania infection. Here, we evaluated the effect of Lutzomyia longipalpis salivary gland sonicate (SGS) on neutrophil and monocyte recruitment and activation of eicosanoid production in a murine model of inflammation. METHODS...

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Veröffentlicht in:Parasit Vectors
Hauptverfasser: Araújo-Santos, Théo, Prates, Deboraci Brito, França-Costa, Jaqueline, Luz, Nívea F, Andrade, Bruno B, Miranda, José Carlos, Brodskyn, Claudia I, Barral, Aldina, Bozza, Patrícia T, Borges, Valéria Matos
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282730/
https://ncbi.nlm.nih.gov/pubmed/25526785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-014-0601-8
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