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Presynaptic pH and vesicle fusion in Drosophila larvae neurones

Both intracellular pH (pH(i)) and synaptic cleft pH change during neuronal activity yet little is known about how these pH shifts might affect synaptic transmission by influencing vesicle fusion. To address this we imaged pH- and Ca(2+)-sensitive fluorescent indicators (HPTS, Oregon green) in bouton...

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Détails bibliographiques
Publié dans:Synapse
Auteurs principaux: Caldwell, Lesley, Harries, Peter, Sydlik, Sebastian, Schwiening, Christof J
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282566/
https://ncbi.nlm.nih.gov/pubmed/23649934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21678
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