Peritoneal Milky Spots Serve as a Hypoxic Niche and Favor Gastric Cancer Stem/Progenitor Cell Peritoneal Dissemination Through Hypoxia-Inducible Factor 1α

Peritoneal dissemination is the most common cause of death in gastric cancer patients. The hypoxic microenvironment plays a major role in controlling the tumor stem cell phenotype and is associated with patients' prognosis through hypoxia-inducible factor-1α (HIF-1α), a key transcriptional fact...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Miao, Zhi-Feng, Wang, Zhen-Ning, Zhao, Ting-Ting, Xu, Ying-Ying, Gao, Jian, Miao, Feng, Xu, Hui-Mian
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Cancer Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282537/
https://ncbi.nlm.nih.gov/pubmed/25142304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1816
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