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Molecular dynamics of the P450cam–Pdx complex reveals complex stability and novel interface contacts

Cytochrome P450cam catalyzes the stereo and regiospecific hydroxylation of camphor to 5-exo-hydroxylcamphor. The two electrons for the oxidation of camphor are provided by putidaredoxin (Pdx), a Fe(2)S(2) containing protein. Two recent crystal structures of the P450cam–Pdx complex, one solved with t...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Hollingsworth, Scott A, Poulos, Thomas L
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282411/
https://ncbi.nlm.nih.gov/pubmed/25307478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2583
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