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Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma
BACKGROUND: Tryptase, a major secretory product of human mast cells has been implicated as a key mediator of allergic inflammation. Genetic variation in the tryptases is extensive, and α-tryptase, an allelic variant of the more extensively studied β-tryptase, is absent in substantial numbers of the...
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| Publicado en: | Clin Exp Allergy |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282335/ https://ncbi.nlm.nih.gov/pubmed/24372627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12259 |
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