RNA Polymerase II Inhibitor, α-Amanitin, Affects Gene Expression for Gap Junctions and Metabolic Capabilities of Cumulus Cells, but Not Oocyte, during in vitro Mouse Oocyte Maturation

A specific inhibitor of RNA polymerase II, α-amanitin is broadly used to block transcriptional activities in cells. Previous studies showed that α-amanitin affects in vitro maturation of cumulus-oocyte-complex (COC). In this study, we evaluated the target of α-amanitin, and whether it affects oocyte...

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Vydáno v:Dev Reprod
Hlavní autoři: Park, Min-Woo, Lee, Hyun-Seo, Kim, Eun-Young, Lee, Kyung-Ah
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society of Developmental Biology 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282216/
https://ncbi.nlm.nih.gov/pubmed/25949122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12717/DR.2013.17.1.063
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