Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth

Loss of Foxc1 is associated with Dandy-Walker malformation, the most common human cerebellar malformation characterized by cerebellar hypoplasia and an enlarged posterior fossa and fourth ventricle. Although expressed in the mouse posterior fossa mesenchyme, loss of Foxc1 non-autonomously induces a...

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Publicado en:eLife
Autores principales: Haldipur, Parthiv, Gillies, Gwendolyn S, Janson, Olivia K, Chizhikov, Victor V, Mithal, Divakar S, Miller, Richard J, Millen, Kathleen J
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281880/
https://ncbi.nlm.nih.gov/pubmed/25513817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03962
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