Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings

BACKGROUND:  Amphotericin B is the preferred treatment for cryptococcal meningitis, but it has cumulative severe side effects, including nephrotoxicity, hypokalemia, and hypomagnesemia. Amphotericin-induced severe hypokalemia may predispose the patient to cardiac arrhythmias and death, and there is...

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Pubblicato in:Open Forum Infect Dis
Autori principali: Bahr, Nathan C., Rolfes, Melissa A., Musubire, Abdu, Nabeta, Henry, Williams, Darlisha A., Rhein, Joshua, Kambugu, Andrew, Meya, David B., Boulware, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Major Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281785/
https://ncbi.nlm.nih.gov/pubmed/25734140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofu070
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