Molecular Insights into the Coding Region Determinant-binding Protein-RNA Interaction through Site-directed Mutagenesis in the Heterogeneous Nuclear Ribonucleoprotein-K-homology Domains

The ability of its four heterogeneous nuclear RNP-K-homology (KH) domains to physically associate with oncogenic mRNAs is a major criterion for the function of the coding region determinant-binding protein (CRD-BP). However, the particular RNA-binding role of each of the KH domains remains largely u...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Barnes, Mark, van Rensburg, Gerrit, Li, Wai-Ming, Mehmood, Kashif, Mackedenski, Sebastian, Chan, Ching-Man, King, Dustin T., Miller, Andrew L., Lee, Chow H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281763/
https://ncbi.nlm.nih.gov/pubmed/25389298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614735
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