Structural Insight into Amino Group-carrier Protein-mediated Lysine Biosynthesis: CRYSTAL STRUCTURE OF THE LYSZ·LYSW COMPLEX FROM THERMUS THERMOPHILUS

In the biosynthesis of lysine by Thermus thermophilus, the metabolite α-ketoglutarate is converted to the intermediate α-aminoadipate (AAA), which is protected by the 54-amino acid acidic protein LysW. In this study, we determined the crystal structure of LysZ from T. thermophilus (TtLysZ), an amino...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Yoshida, Ayako, Tomita, Takeo, Fujimura, Tsutomu, Nishiyama, Chiharu, Kuzuyama, Tomohisa, Nishiyama, Makoto
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281745/
https://ncbi.nlm.nih.gov/pubmed/25392000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595983
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