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HMGB1 exacerbates renal tubulointerstitial fibrosis through facilitating M1 macrophage phenotype at the early stage of obstructive injury

Previous studies have indicated that macrophage phenotype diversity is involved in the progression of renal fibrosis. However, the factors facilitating M1 or M2 phenotypes and the function of these polarized macrophages in kidney injury and fibrosis remain largely unknown. In the present study, we f...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Tian, Shaojiang, Zhang, Lansing, Tang, Junming, Guo, Xia, Dong, Kun, Chen, Shi-You
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281691/
https://ncbi.nlm.nih.gov/pubmed/25377911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00484.2014
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