Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin

Present study investigated the potential effects of Ferula asafetida resin on metabolic activities of human drug metabolizing enzymes: CYP2D6 and CYP3A4. Dextromethorphan (DEX) was used as a marker to assess metabolic activities of these enzymes, based on its CYP2D6 and CYP3A4 mediated metabolism to...

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Bibliografische gegevens
Gepubliceerd in:Saudi Pharm J
Hoofdauteurs: Al-Jenoobi, Fahad I., Al-Thukair, Areej A., Alam, Mohd Aftab, Abbas, Fawkeya A., Al-Mohizea, Abdullah M., Alkharfy, Khalid M., Al-Suwayeh, Saleh A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281599/
https://ncbi.nlm.nih.gov/pubmed/25561870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2014.03.004
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