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Effect of ingested lipids on drug dissolution and release with concurrent digestion: a modeling approach

PURPOSE: To mechanistically study and model the effect of lipids, either from food or self-emulsifying drug delivery systems (SEDDS), on drug transport in the intestinal lumen. METHODS: Simultaneous lipid digestion, dissolution/release, and drug partitioning were experimentally studied and modeled f...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Buyukozturk, Fulden, Di Maio, Selena, Budil, David E., Carrier, Rebecca L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281523/
https://ncbi.nlm.nih.gov/pubmed/24234918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1238-6
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