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Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

Cancer therapeutics is evolving to precision medicine, with the goal of matching targeted compounds with molecular aberrations underlying a patient’s cancer. While murine models offer a pre-clinical tool, associated costs and time are not compatible with actionable patient-directed interventions. Us...

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Detalles Bibliográficos
Publicado en:Haematologica
Main Authors: Bentley, Victoria L., Veinotte, Chansey J., Corkery, Dale P., Pinder, Jordan B., LeBlanc, Marissa A., Bedard, Karen, Weng, Andrew P., Berman, Jason N., Dellaire, Graham
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281315/
https://ncbi.nlm.nih.gov/pubmed/25281505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.110742
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