Granulocyte Colony-Stimulating Factor Reduces Fibrosis in a Mouse Model of Chronic Pancreatitis

BACKGROUND: Chronic pancreatitis (CP) is a necroinflammatory process resulting in extensive pancreatic fibrosis. Granulocyte colony-stimulating factor (G-CSF), a hematopoietic stem cell mobilizer, has been shown to exert an anti-fibrotic effect partly through the enrichment of bone marrow (BM) cells...

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Vydáno v:PLoS One
Hlavní autoři: Lin, Wey-Ran, Yen, Tzung-Hai, Lim, Siew-Na, Perng, Ming-Der, Lin, Chun-Yen, Su, Ming-Yo, Yeh, Chau-Ting, Chiu, Cheng-Tang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281240/
https://ncbi.nlm.nih.gov/pubmed/25551560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116229
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